RESEARCH INTERESTs

Millions of people worldwide suffer bone loss due to injury, infection, disease or abnormal skeletal development, and treatment frequently requires regeneration of new bone. Since each patient has only a limited amount of bone available for grafting, the demand for synthetic bone substitutes is high. Those currently available are far from optimal, but Professor Hala Zreiqat has developed a unique ceramic material that acts as a scaffold on which the body can regenerate new bone, then gradually degrades as it is replaced by natural bone.

"The bone substitute my team and I have developed resembles natural bone in terms of architecture, strength and porosity. So it is strong enough to withstand the loads that will be applied to it, and also contains pores that allow blood and nutrients to penetrate it. In this way it is designed to encourage normal bone growth, and to eventually be replaced by natural bone in the body.

"The fact that it actually 'kick starts' the process of bone regeneration makes it far superior to other available materials. Our tests also show that it will not be rejected by the body. In addition, we can make as many implants as we want from this material, so availability will not be a problem.

"This material has the potential to positively affect the quality of life of millions of people globally, so we are hoping to see it in use clinically within the next 10 years.

FUNDED RESEARCH

  • GRANT
    Bioartificial Tendon Engineering for Optimised CellMaterialInteraction in Musculo-Skeletal Repair (BioTengineer)
    Universities Australia6 Mar 2026
    People funded by this grant:
    • Zreiqat H
  • GRANT
    Hyperboloidal Curvature as a Novel Stem Cell Senescence Regulator
    Australian Research Council (ARC)31 Jan 2025 - 30 Jan 2028
    People funded by this grant:
    • Zreiqat H
  • GRANT
    Swiss National Science Foundation1 Jul 2024 - 30 Jun 2028
    People funded by this grant:
    • Zenobi-Wong M,
    • Zeiter S,
    • Zreiqat H,
    • Baldi L,
    • Hui IB
  • GRANT
    BIOTech Futures Symposium
    Department of Enterprise, Investment and Trade (DEIT)1 Jan 2023
    People funded by this grant:
    • Zreiqat H
  • GRANT
    Interface structures mediating load transfer between soft and hard tissues
    Australian Research Council (ARC)1 Jan 2023 - 31 Dec 2025
    People funded by this grant:
    • Zreiqat H
  • GRANT
    DEVELOPMENT OF PHOTORECEPTOR CELL THERAPY TO TREAT BLINDNESS
    Department of Health and Aged Care (Federal - administered by NHMRC)1 Jun 2022 - 31 May 2027
    People funded by this grant:
  • GRANT
    Council for International Exchange of Scholars1 Jun 2022 - 30 Sep 2022
    People funded by this grant:
    • Zreiqat H,
    • Langer R
  • GRANT
    Australian Research Council13 Apr 2022 - 31 Dec 2023
    People funded by this grant:
    • Molloy M,
    • Halliday G,
    • Zreiqat H,
    • Yang J,
    • Sue C
  • GRANT
    An anti-senescence nanoplatform and its underlying mechanism
    Australian Research Council (ARC)1 Mar 2022 - 28 Feb 2026
    People funded by this grant:
    • Lu Z,
    • Zreiqat H,
    • Singh G
  • GRANT
    3-D Nanoprinting project
    Nano Institute1 Jan 2022
    People funded by this grant:
    • Zreiqat H
  • GRANT
    3D Two-Photon Nanoprinter for Advanced Multi-Functional Materials and Devices
    Australian Research Council (ARC)1 Jan 2021 - 31 Dec 2021
    People funded by this grant:
    • Zreiqat H
  • GRANT
    Advanced mechanical property testing suite
    Australian Research Council (ARC)1 Jan 2019 - 28 Feb 2021
    People funded by this grant:
  • GRANT
    Magnetic Hyperthermia Facility: Magnetic Nanotechnology for Bioimaging andTherapeutic Applications
    National Health and Medical Research Council (NHMRC)1 Jan 2019
    People funded by this grant:
    • Zreiqat H,
    • Singh G,
    • Martinez-Martin D
  • GRANT
    Novel 3D printed scaffolds for intervertebral fusion
    National Health and Medical Research Council (NHMRC)1 Jan 2019
    People funded by this grant:
    • Zreiqat H,
    • Li Q,
    • Dunstan C
  • GRANT
    Xenograft using Kangaroo Tendon as a substitute for ligament reconstruction in the human population - Innovative Manufacturing CRC Limited, Bone Ligament Tendon BLT and Allegra Orthopaedics
    Innovative Manufacturing CRC (IMCRC)1 Aug 2018
    People funded by this grant:
  • GRANT
    2018 Australia-Harvard Fellowships
    Harvard Club of Australia Foundation1 Jan 2018
    People funded by this grant:
    • Rutkove S,
    • Zreiqat H
  • GRANT
    A new collaborative strategy for treating joint injury to prevent osteoarthritis
    University of Sydney1 Jan 2018
    People funded by this grant:
  • GRANT
    A novel strategy for treating chronic joint injury
    Arthritis Foundation of Australia1 Jan 2018
    People funded by this grant:
  • GRANT
    B3D Cervical Interbody Fusion Device
    MTP Connect1 Jan 2018
    People funded by this grant:
    • Zreiqat H
  • GRANT
    High-throughput Portable and Wearable Device Fabrication Facility
    Australian Research Council (ARC)1 Jan 2018 - 31 Dec 2019
    People funded by this grant:
    • Jin D,
    • Zreiqat H,
    • Fazekas de St Groth BD
  • GRANT
    Optimising bone regeneration using advanced design and fabrication technologies
    National Health and Medical Research Council (NHMRC)1 Jan 2018 - 31 Dec 2020
    People funded by this grant:
  • GRANT
    Structure-mimicking synthetic scaffolds for tendon and ligament repair
    Universities Australia1 Jan 2018
    People funded by this grant:
    • Zreiqat H
  • GRANT
    Xenograft using Kangaroo Tendon/Tail as a substitute for ligament reconstruction in the human population
    Innovative Manufacturing CRC (IMCRC)1 Jan 2018
    People funded by this grant:
  • GRANT
    ARC Training Centre for Innovative BioEngineering
    NSW Department of Industry1 Jul 2017
    People funded by this grant:
    • Zreiqat H
  • GRANT
    ARC Training Centre for Innovative BioEngineering
    Australian Research Council (ARC)1 Jul 2017 - 30 Jun 2022
    People funded by this grant: