Research projects & supervision summary

Project Opportunities

Title: Precision biomanufacturing of multifuctional extracelluar vesicles/biologicals.

Summary of opportunity:

 

We are seeking a talented, highly skilled and motivated candidate to undertake an industry-directed PhD project that aims to develop the precision biomanufacturing processes of next-generation functional biologicals for clinical applications.

 

Opportunity synopsis:

 

We have an open position for a talented, highly skilled and motivated PhD candidate to undertake an industry-directed project that will involve an end-to-end approach to developing an understanding of the microenvioronment conditions that influence the myriad of metabolic outputs derived from probiotic fermentation and establish a framework for the biocharacterisation of the complex matrix of biologicals' components.

This project aims to develop multi-omic methodologies to characterise the assembly of biologiclas. The work will seek to identify the significant components of the next-generation functional materials (NGFM) and streamline methods for characterisation, quantification, and ultimately, standardisation of the outputs for industrial application. During this project, the candidate will work at the interface between industry and academia and have access to state-of-the-art Nano-Bio-Characterisation and Biofabrication facilities at the University of Sydney and industry partner to produce and characterise new classes of biologicals utilising microbial biofactories.

The candidate will get to work closely with the industry partner and realise the potential applications of the NGFMs with a view to the development of application-specific protocols for use in the industry. The candidate should have a strong background in bioprocessing, biomedical sciences, and microbiological sciences. An Honours or Master by research qualification is preferred for the applicant due to the advanced nature of the project and the high level of understanding and laboratory skills required to excel in this project.

 

RESEARCH PROJECTS & ACTIVITIES

  • RESEARCH-BASED DEGREE SUPERVISION
    Advancing in-vitro blood-brain barrier models using lipid-based nanoparticles as a strategy for drug delivery
  • RESEARCH-BASED DEGREE SUPERVISION
    Bioproduction and Bioprocessing of Probiotic Extracellular Vesicle as Multifunctional Therapeutics
  • RESEARCH-BASED DEGREE SUPERVISION
    Cell culture strategies and natural-origin polymers
  • RESEARCH-BASED DEGREE SUPERVISION
    Develop a high yield bioprocessing system to produce collagen from mammalian cells
  • RESEARCH-BASED DEGREE SUPERVISION
    Development of an extracellular vesicle-laden hydrogel dressings for chronic wound
  • RESEARCH-BASED DEGREE SUPERVISION
    Development of cannabinoid loaded nanoparticles and advanced materials to enable new horizons for toxicity screening
  • RESEARCH-BASED DEGREE SUPERVISION
    Development of electrospun fiber bundles from tropoelastin based composites for ligament regeneration
  • RESEARCH-BASED DEGREE SUPERVISION
    Development of therapeutic extracellular vesicles for the treatment of acute and chronic lung diseases
  • RESEARCH-BASED DEGREE SUPERVISION
    Effects of Humidity and Excipients on Aerosol Performance and Electrostatic Charge of Spray-dried Powders for Inhalation
  • RESEARCH-BASED DEGREE SUPERVISION
    Gallium nanoparticle as an antimicrobial agent to combat antibiotic resistance
  • RESEARCH-BASED DEGREE SUPERVISION
    Ion implanted 'Trojan horse' surfaces with antimicrobial activity
  • RESEARCH-BASED DEGREE SUPERVISION
    Laboratory and Clinical Development of a Novel Thymosin-based Polymer Hydrogel for Trabecular and Cortical Bone Regeneration of the Jaw
  • RESEARCH-BASED DEGREE SUPERVISION
    Modulation & Comparative Analysis of Small Hydrophilic Molecules Release Mechanisms from Hybrid ‘Liposome-Polymer Macrogel’ Systems
  • RESEARCH-BASED DEGREE SUPERVISION
    Precision biomanufacturing of postbiotics: the next-generation functional materials for pharmaceutical nutraceutical food and agriculture applications.
  • RESEARCH-BASED DEGREE SUPERVISION
    Skin Tissue Engineering in Burns & Reconstructive Surgery: From Cells to Surgery and the Clinical Impact of Soft Tissue Engineering
  • RESEARCH-BASED DEGREE SUPERVISION
    The EV-phage Biobots – unraveling natural synergies of extracellular vesicles and bacteriophage as a multifunctional therapeutic agent for infected skin wounds
  • RESEARCH-BASED DEGREE SUPERVISION
    The EV-phage Biobots – unraveling therapeutic effect of extracellular vesicles-bacteriophage conjugate for skin infections and rare skin conditions
  • RESEARCH-BASED DEGREE SUPERVISION
    Ultrasound-Propelled Nano-Enabled Drug Delivery Systems for Lung Cancer Treatment
  • RESEARCH-BASED DEGREE SUPERVISION
    Validation of IRBP as a retinal treatment target and screening for human photoreceptor-specific nanoparticles for CRISPRa gene therapy
  • RESEARCH-BASED DEGREE SUPERVISION
    Veterinary applications of Nano-enhanced High Intensity Focused Ultrasound (HIFUn+) as a platform technology for Drug Delivery