ProfessorStephen Simpson
NHMRC Investigator Fellow
Faculty of Science
- NHMRC Investigator FellowFaculty of Science
RESEARCH INTERESTs
Stephen Simpson, together with David Raubenheimer, developed an integrative modelling framework for nutrition (the Geometric Framework), which was devised and tested using insects. This has since been applied to a wide range of organisms, from slime moulds to humans, and problems, from aquaculture and conservation biology to the dietary causes of human obesity and ageing. He has also revolutionised understanding of swarming in locusts, with research spanning neurochemical events within the brains of individual locusts to continental-scale mass migration.
Stephen also leads the Precision Nutrition research group. The group's emphasis is 'bottom-up', in that we are especially concerned with the way in which lower-level processes lead to higher level outcomes. The approach focuses on the behaviour of individual organisms and involves an interplay between theory and experiment. Most of our experimental work is on mice, although recent work has examined fish, birds and other mammals - including humans. Techniques employed include the quantitative analysis of behaviour, neurophysiology, metabolic and digestive physiology, mathematical modelling, computer simulations and laboratory selection experiments.
Stephen's research aligns with the Faculty of Science Research Strengths - Complex Systems, Understanding Life on Earth, Brain Behaviour and Cognition, Fundamental Laws of Nature, Future Foods, Data and Decisions.
FUNDED RESEARCH
- GRANTMetabolic Steatohepatitis (MeSH): From understanding and detecting disease to liver transplantationSnow Medical Research Foundation Ltd1 Apr 2026People funded by this grant:
- Strasser S,
- George J,
- McCaughan GW,
- Simpson S,
- Blementhal A
- GRANTNode Award SimpsonSydney Policy Lab1 Jan 2026People funded by this grant:
- Simpson S
- GRANTOptimising Nutrition for Healthy AgeingCharles Perkins Centre9 Jan 2025People funded by this grant:
- Simpson S
- GRANTThe Nutritional Geometry of Immunity, Obesity and AppetiteNational Health and Medical Research Council (NHMRC)1 Jan 2025People funded by this grant:
- Simpson S
- GRANTTo support research by the University and currently at the Charles Perkins Centre in the field of maternal nutrition during pregnancy, including ancillary costsHooper Shaw Foundation1 Jan 2025People funded by this grant:
- Simpson S
- GRANTPaving the way for ultra-long haul flights: strategies to mitigate jetlagAustralian Research Council (ARC)5 Aug 2024 - 4 Aug 2027People funded by this grant:
- De Chazal P,
- Capps P,
- Van Dongen HPA,
- Postnova S,
- Sletten T
- GRANTAdaptive Policy System joint node with the Charles Perkins CentreSydney Policy Lab1 Jan 2024People funded by this grant:
- Simpson S
- GRANTIn utero saccharide exposure: Revisiting the provenance of hypertrophic cardiomyopathyNSW Health1 Jul 2023People funded by this grant:
- Wang X,
- Simpson S,
- Ding DM,
- Francois M,
- Gordon A
- GRANTStrathfield Preventative Health ProjectGoogle Asia Pacific Pte. Ltd1 Jan 2023People funded by this grant:
- Simpson S
- GRANTPathways to benefit for Indigenous Australians in Genomic MedicineDepartment of Health and Aged Care (Federal - administered by NHMRC)1 Jun 2022People funded by this grant:
- Huebner S,
- Simpson S,
- Pearson G,
- Bryant V,
- Hermes A
- GRANTAustralian Eating Disorders Research & Translation CentreDepartment of Health and Aged Care (Federal)1 Apr 2022People funded by this grant:
- Touyz S,
- Marks P,
- Simpson S,
- Maguire SL,
- Hickie I
- GRANTDefining and treating the physiological effects of bushfire smoke exposureMedical Research Future Fund1 Jun 2020 - 31 May 2024People funded by this grant:
- Hansbro P,
- Wark P,
- Jenkins C,
- Simpson S,
- Donovan C
- GRANTAncestral causes of obesity: Understanding epigenetic transmission by spermatozoaNovo Nordisk Foundation8 Jul 2019People funded by this grant:
- Barres R,
- Simpson S
- GRANTBioDAQ E3 home-cage food and liquid intake and phenotypic assessment systemDVC Research1 Jan 2019People funded by this grant:
- Raubenheimer D,
- Simpson S,
- Solon-Biet S
- GRANTNutrition and ComplexityNational Health and Medical Research Council (NHMRC)1 Jan 2019 - 31 Dec 2023People funded by this grant:
- Gunton JE,
- Raubenheimer D,
- George J,
- Le Couteur D,
- Simpson S
- GRANTCRC: Alertness CRC - PQ1.1.18- B787FATIGUE - Institute for Breathing and Sleep (IBAS), Woolcock Institute & Monash Uni - Stephen SimpsonAlertness CRC Ltd1 Jan 2018People funded by this grant:
- Simpson S
- GRANTNorthern Norway Regional Health Authority1 Jan 2018People funded by this grant:
- Zykova S,
- Holmes A,
- Simpson S,
- Ness C,
- Ytrehus K
- GRANTNutritional and bacterial influences on gut and peripheral homeostasisAustralian Research Council (ARC)15 Jun 2017 - 14 Jun 2021People funded by this grant:
- Ashton J,
- Mackay C,
- Macia L,
- Simpson S
- GRANTCanadian Institutes of Health Research1 Apr 2017 - 31 Mar 2022People funded by this grant:
- Gaudreau P,
- Payette H,
- Presse N,
- Cohen AA,
- Milot E
- GRANTA multiple ion beam facility for Microscopy and NanofabricationAustralian Research Council (ARC)1 Jan 2017 - 31 Dec 2018People funded by this grant:
- Simpson S,
- Wallace G,
- Bradby JE,
- James D,
- Shadrivov IV
- GRANTDetermining the macronutrient composition of the optimum diet for the management of type 2 diabetesDiabetes Australia1 Jan 2017People funded by this grant:
- Simpson S,
- Le Couteur D,
- Cogger VC,
- Wali J
- GRANTResearch support for Academic Director Charles Perkins Centres (CPC) (DVCR-725)DVC Research1 Jan 2017People funded by this grant:
- Simpson S
- GRANTMaking Green Guard greener: enhancing the efficacy of a biopesticideAustralian Research Council (ARC)22 Feb 2016 - 30 Jun 2018People funded by this grant:
- Holmes E,
- Buhl J,
- Woodman J,
- Wilson K,
- Simpson S
- GRANTIs FGF21 the master regulator of protein intake?Australian Research Council (ARC)4 Jan 2016People funded by this grant:
- Le Couteur D,
- Conigrave A,
- Simpson S,
- James D,
- Raubenheimer D