RESEARCH INTERESTs

Stephen Simpson, together with David Raubenheimer, developed an integrative modelling framework for nutrition (the Geometric Framework), which was devised and tested using insects. This has since been applied to a wide range of organisms, from slime moulds to humans, and problems, from aquaculture and conservation biology to the dietary causes of human obesity and ageing. He has also revolutionised understanding of swarming in locusts, with research spanning neurochemical events within the brains of individual locusts to continental-scale mass migration.

Stephen also leads the Precision Nutrition research group. The group's emphasis is 'bottom-up', in that we are especially concerned with the way in which lower-level processes lead to higher level outcomes. The approach focuses on the behaviour of individual organisms and involves an interplay between theory and experiment. Most of our experimental work is on mice, although recent work has examined fish, birds and other mammals - including humans. Techniques employed include the quantitative analysis of behaviour, neurophysiology, metabolic and digestive physiology, mathematical modelling, computer simulations and laboratory selection experiments.

Stephen's research aligns with the Faculty of Science Research Strengths - Complex Systems, Understanding Life on Earth, Brain Behaviour and Cognition, Fundamental Laws of Nature, Future Foods, Data and Decisions.

FUNDED RESEARCH

  • GRANT
    Metabolic Steatohepatitis (MeSH): From understanding and detecting disease to liver transplantation
    Snow Medical Research Foundation Ltd1 Apr 2026
    People funded by this grant:
  • GRANT
    Node Award Simpson
    Sydney Policy Lab1 Jan 2026
    People funded by this grant:
    • Simpson S
  • GRANT
    Optimising Nutrition for Healthy Ageing
    Charles Perkins Centre9 Jan 2025
    People funded by this grant:
    • Simpson S
  • GRANT
    The Nutritional Geometry of Immunity, Obesity and Appetite
    National Health and Medical Research Council (NHMRC)1 Jan 2025
    People funded by this grant:
    • Simpson S
  • GRANT
    To support research by the University and currently at the Charles Perkins Centre in the field of maternal nutrition during pregnancy, including ancillary costs
    Hooper Shaw Foundation1 Jan 2025
    People funded by this grant:
    • Simpson S
  • GRANT
    Paving the way for ultra-long haul flights: strategies to mitigate jetlag
    Australian Research Council (ARC)5 Aug 2024 - 4 Aug 2027
    People funded by this grant:
  • GRANT
    Adaptive Policy System joint node with the Charles Perkins Centre
    Sydney Policy Lab1 Jan 2024
    People funded by this grant:
    • Simpson S
  • GRANT
    In utero saccharide exposure: Revisiting the provenance of hypertrophic cardiomyopathy
    NSW Health1 Jul 2023
    People funded by this grant:
  • GRANT
    Strathfield Preventative Health Project
    Google Asia Pacific Pte. Ltd1 Jan 2023
    People funded by this grant:
    • Simpson S
  • GRANT
    Pathways to benefit for Indigenous Australians in Genomic Medicine
    Department of Health and Aged Care (Federal - administered by NHMRC)1 Jun 2022
    People funded by this grant:
    • Huebner S,
    • Simpson S,
    • Pearson G,
    • Bryant V,
    • Hermes A
  • GRANT
    Australian Eating Disorders Research & Translation Centre
    Department of Health and Aged Care (Federal)1 Apr 2022
    People funded by this grant:
  • GRANT
    Defining and treating the physiological effects of bushfire smoke exposure
    Medical Research Future Fund1 Jun 2020 - 31 May 2024
    People funded by this grant:
    • Hansbro P,
    • Wark P,
    • Jenkins C,
    • Simpson S,
    • Donovan C
  • GRANT
    Ancestral causes of obesity: Understanding epigenetic transmission by spermatozoa
    Novo Nordisk Foundation8 Jul 2019
    People funded by this grant:
    • Barres R,
    • Simpson S
  • GRANT
    BioDAQ E3 home-cage food and liquid intake and phenotypic assessment system
    DVC Research1 Jan 2019
    People funded by this grant:
  • GRANT
    Nutrition and Complexity
    National Health and Medical Research Council (NHMRC)1 Jan 2019 - 31 Dec 2023
    People funded by this grant:
  • GRANT
    CRC: Alertness CRC - PQ1.1.18- B787FATIGUE - Institute for Breathing and Sleep (IBAS), Woolcock Institute & Monash Uni - Stephen Simpson
    Alertness CRC Ltd1 Jan 2018
    People funded by this grant:
    • Simpson S
  • GRANT
    Northern Norway Regional Health Authority1 Jan 2018
    People funded by this grant:
    • Zykova S,
    • Holmes A,
    • Simpson S,
    • Ness C,
    • Ytrehus K
  • GRANT
    Nutritional and bacterial influences on gut and peripheral homeostasis
    Australian Research Council (ARC)15 Jun 2017 - 14 Jun 2021
    People funded by this grant:
    • Ashton J,
    • Mackay C,
    • Macia L,
    • Simpson S
  • GRANT
    Canadian Institutes of Health Research1 Apr 2017 - 31 Mar 2022
    People funded by this grant:
    • Gaudreau P,
    • Payette H,
    • Presse N,
    • Cohen AA,
    • Milot E
  • GRANT
    A multiple ion beam facility for Microscopy and Nanofabrication
    Australian Research Council (ARC)1 Jan 2017 - 31 Dec 2018
    People funded by this grant:
    • Simpson S,
    • Wallace G,
    • Bradby JE,
    • James D,
    • Shadrivov IV
  • GRANT
    Cellular Heterogeneity in Health, Aging and Disease
    DVC Research1 Jan 2017
    People funded by this grant:
  • GRANT
    Determining the macronutrient composition of the optimum diet for the management of type 2 diabetes
    Diabetes Australia1 Jan 2017
    People funded by this grant:
  • GRANT
    Research support for Academic Director Charles Perkins Centres (CPC) (DVCR-725)
    DVC Research1 Jan 2017
    People funded by this grant:
    • Simpson S
  • GRANT
    Making Green Guard greener: enhancing the efficacy of a biopesticide
    Australian Research Council (ARC)22 Feb 2016 - 30 Jun 2018
    People funded by this grant:
    • Holmes E,
    • Buhl J,
    • Woodman J,
    • Wilson K,
    • Simpson S
  • GRANT
    Is FGF21 the master regulator of protein intake?
    Australian Research Council (ARC)4 Jan 2016
    People funded by this grant: