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ProfessorMark Douglas

Professor of Infectious Diseases and Hepatic Medicine

Faculty of Medicine and Health

Orcid identifier0000-0003-4621-3485 (opens in a new tab)⁠
  • Professor of Infectious Diseases and Hepatic Medicine
    Faculty of Medicine and Health

RESEARCH INTERESTs

Professor Douglas undertakes basic and translational research on hepatitis B virus (HBV), hepatitis C virus (HCV) and hepatitis D virus (HDV) pathogenesis. His research investigates interactions between hepatitis viruses and their host, focusing on metabolic pathways, cell signalling, innate immunity and induction of liver cancer. He uses novel cellular models to study how virus-host interactions affect virus replication, liver inflammation, liver fibrosis and development of liver cancer.

The aims of his research are to develop new treatments to combat viral hepatitis and use personalised medicine approaches to improve response to current antiviral therapies.

FUNDED RESEARCH

  • GRANT
    Cyclic peptide-based assays to increase access to hepatitis B diagnosis and testing
    Department of Health and Aged Care (Federal)1 Jan 2023
    People funded by this grant:
  • GRANT
    Building active surveillance systems to track hepatitis C virusepidemiology and antiviral resistance
    Australian Centre for HIV and Hepatitis Virology Research (ACH2)1 Jan 2022
    People funded by this grant:
  • GRANT
    Development of a diagnostic assay to measure hepatitis B virus cccDNA
    Australian Centre for HIV and Hepatitis Virology Research (ACH2)1 Jan 2021
    People funded by this grant:
  • GRANT
    Inhibiting host TM6SF2 to cure Hepatitis B
    National Health and Medical Research Council (NHMRC)1 Jan 2021 - 31 Dec 2023
    People funded by this grant:
  • GRANT
    Quantifying integrated and episomal HBV DNA in fine needle aspirate liver biopsies
    Australian Centre for HIV and Hepatitis Virology Research (ACH2)1 Jan 2020
    People funded by this grant:
  • GRANT
    Developing a novel diagnostic test for hepatitis C virus drug resistance
    Australian Centre for HIV and Hepatitis Virology Research (ACH2)1 Jul 2016
    People funded by this grant:
  • GRANT
    Hepatitis B Virus Genomic Variations and Development of Hepatocellular Carcinoma
    DVC Research1 Jan 2014
    People funded by this grant:
    • Douglas M,
    • Khan A
  • GRANT
    A pilot study of fenofibrate to improve hepatitis C virus treatment response - Australian Centre for HIV and Hepatitis Virology Research (ACH2)
    Commonwealth Department of Health and Ageing1 Jul 2013
    People funded by this grant:
  • GRANT
    Staying Strong and Staying On A Psychosocial Screening Tool to Improve Uptake of HCV Treatment
    Gilead Sciences Ptd Ltd1 Jul 2013
    People funded by this grant:
    • Douglas M
  • GRANT
    Characterization of ARL6IP5 in hepatitis C-related liver cancer
    National Health and Medical Research Council (NHMRC)1 Jan 2013 - 31 Dec 2016
    People funded by this grant:
  • GRANT
    Developing functional research partnerships and student exchange, focused on relevant infectious diseases with the Eijkman Institute and Hasanuddin University, Indonesia
    DVC International6 May 2012
    People funded by this grant:
  • GRANT
    The role of endocannabinoids in chronic hepatitis C
    National Health and Medical Research Council (NHMRC)1 Jan 2011 - 31 Dec 2013
    People funded by this grant:
  • GRANT
    mechanisms of metabolic complications in chronic hepatitis C virus infection
    Millennium Foundation Ltd1 Jan 2008
    People funded by this grant:
    • Douglas M
  • GRANT
    The Influence Of Hepatitis C Virus Genotype On Hepatic Lipid Metabolism
    National Health and Medical Research Council (NHMRC)1 Jan 2005 - 31 Dec 2009
    People funded by this grant:
    • Douglas M