RESEARCH INTERESTs

My research group, Sydney Brainomics is a multi-disciplinary group that brings together neuropathology, molecular biology and bioinformatics to study neurodegenerative diseases including Alzheimer's disease (AD) and alcohol-related brain damage (ARBD). Sydney Brainomics combines spatial and molecular data from human postmortem brain tissue to improve our understanding of why certain individuals get these diseases and how to cure them. We are also involved in international and national collaborative teams that utilise data science, machine learning, neuroimaging, patient-derived stem cells and transgenic animal models towards these goals. We have current collaborations with researchers at Brown University, Ohio State University, University of North Carolina, Indiana University, Korea Brain Bank Institute, and the University of Auckland. I am also the Leader of the 'Neurobiology' research node at the Charles Perkins Centre that aims to understand the bidirectional relationships between brains diseases like AD and systemic chronic disorders such as cardiovascular disease, type 2 diabetes and obesity using the expertise at the Charles Perkins Centre and beyond. 

FUNDED RESEARCH

  • GRANT
    Link between Diabetes and Alzheimer's disease
    Lucas Papaw Foundation8 May 2024
    People funded by this grant:
    • Sutherland G
  • GRANT
    Rewarding Research 2024
    Faculty of Medicine and Health1 Jan 2024
    People funded by this grant:
    • Sutherland G
  • GRANT
    Pathogenesis of Early- Versus Late-Stage Alcohol-Mediated White Matter Degeneration
    National Institutes of Health (USA)1 Apr 2022 - 31 Mar 2027
    People funded by this grant:
    • Sutherland G
  • GRANT
    Brain Single-nuclei and iPS-derived cells transcriptomic analysis to define the
    National Institutes of Health (USA)1 Jan 2021
    People funded by this grant:
    • Sutherland G
  • GRANT
    SOAR Fellowship
    DVC Research1 Jan 2019
    People funded by this grant:
    • Sutherland G
  • GRANT
    Assessing protein level and distribution in Alzheimers disease-affected human brains using matrix assisted laser desorption / ionization (MALDI) imaging mass spectrometry: A methodology to image proteins in tissue without animal-derived antibodies
    Medical Advances Without Animals (MAWA)1 Jul 2016
    People funded by this grant:
  • GRANT
    SMS MCR Accelerator Grant 2016
    Sydney Medical School1 Jan 2016
    People funded by this grant:
    • Sutherland G
  • GRANT
    The microglial transcriptome in health and disease
    Sydney Medical School2 Jan 2015
    People funded by this grant:
    • Sutherland G
  • GRANT
    CLARIOstar Multifunctional Microplate Reader for Shared Used at the Open Access, Multi-User Molecular Biology Core Facility
    National Health and Medical Research Council (NHMRC)1 Jan 2014
    People funded by this grant:
  • GRANT
    Brain Tissue Resource Center for Alcohol Research
    National Institutes of Health (USA)1 Sep 2013 - 31 Aug 2013
    People funded by this grant:
    • Sutherland G
  • GRANT
    QX100 Droplet Digital PCR system for Shared Used at the Open Access, Multi-User Molecular Biology Core Facility
    National Health and Medical Research Council (NHMRC)1 Jan 2013
    People funded by this grant:
  • GRANT
    NOVEL MECHANISMS UNDERLYING THE SPREADING OF TAU PATHOLOGY IN ALZHEIMERS DISEASE AND OTHER TAUOPATHIES
    National Health and Medical Research Council (NHMRC)1 Jan 2012 - 31 Dec 2015
    People funded by this grant:
    • Kril J,
    • Ittner L
  • GRANT
    The role of Neuroglobin in Alzheimers Disease
    The Judith Jane Mason and Harold Stannett Williams Memorial Foundation1 Jan 2012
    People funded by this grant:
  • GRANT
    The Role of Neuroglobin in Alzheimers disease
    Mason Foundation1 Jan 2012
    People funded by this grant:
    • Sutherland G
  • GRANT
    Gliodegeneration in Chronic Alcoholism
    University of Sydney1 Jan 2011
    People funded by this grant:
    • Sutherland G
  • GRANT
    Mitochondrial perturbation in human olfactory-derived cells: A disease model for Parkinson's Disease
    Griffith University1 Jan 2009
    People funded by this grant:
    • Sutherland G
  • GRANT
    Brain Tissue Resource Center for Alcohol Research
    National Institutes of Health (USA)1 Sep 2000 - 30 Jun 2028
    People funded by this grant:
    • Sutherland G