ProfessorDavid Celermajer

Scandrett Professor of Cardiol

Faculty of Medicine and Health

RESEARCH INTERESTs

Congenital heart disease (CHD) is one of the most common birth defects, with an incidence of 75/1000 live births internationally. Advances in surgical and medical care of CHD in children have led to growth in the number of adults living with CHD, especially those with complex heart disease. The changing epidemiology of the CHD population has created a need for improved specialty care for these patients. Professor Celermajer’s team conducts research in both clinical science and public health to help inform clinical treatment and policy concerning adults with CHD.
 
David led the development of the Adult Congenital Heart Disease (ACHD) Database at Royal Prince Alfred Hospital, an essential tool in the clinical care and research of NSW’s largest ACHD population. Specifically, this has enabled research into the characterisation and management of late-stage complications in ACHD, such as pulmonary hypertension, arrhythmias, endocarditis and heart failure. Professor Celermajer’s research also investigates CHD’s impact on other systems in the body, for example, retinal vessel changes in the adults with Coarctation of the Aorta. Appropriate exercise has also been a key focus on improving the outcomes in ACHD patients, particularly in individuals living with a Fontan circulation.
 
From a public health perspective, his research group is interested in developing ‘whole-of-life’ care for patients with CHD. Previous research from his group shows that patients require continuing follow up with specialty CHD clinicians to minimise risk of late-stage complications associated with ACHD. Based on these findings, David’s group has begun to collaborate with various NSW Health districts to demonstrate a model that will provide system-wide ‘whole-of-life’ care for patients with CHD.

FUNDED RESEARCH

  • GRANT
    Detecting and treating silent CAD- innovation for equity and scale
    NSW Health1 Jul 2026
    People funded by this grant:
  • GRANT
    My Heart, My Voice: Implementation of Patient- and Parent-Reported Outcome Measures (PROMs) for children and young people with implantable cardiac devices
    Department of Health and Aged Care (Federal)1 Mar 2026 - 31 May 2030
    People funded by this grant:
    • Celermajer D,
    • Ullman A
  • GRANT
    A Multidisciplinary Lifestyle Program to Enhance CARDIOvascular Health in Young People with Congenital Heart Disease through Exercise and Dietary GuidancE (CARDIO-EDGE)
    NSW Health1 Mar 2025
    People funded by this grant:
  • GRANT
    Creating a National Congenital Heart Disease (CHD) "Knowledge Bank"
    Department of Health and Aged Care (Federal)1 Jan 2025 - 31 Dec 2028
    People funded by this grant:
    • Nicholson C,
    • Ayer J,
    • Celermajer D,
    • Sholler G,
    • Strange G
  • GRANT
    Inhibiting vascular leak using new molecular glues
    National Heart Foundation of Australia1 Jan 2025
    People funded by this grant:
  • GRANT
    Non-invasive imaging of atherosclerotic plaque: quantification of disease activity for improved identification of patients with residual cardiovascular risk
    Department of Health and Aged Care (Federal)1 Jun 2022 - 31 May 2023
    People funded by this grant:
    • Stocker R
  • GRANT
    Understanding the Burden of Congenital Heart Disease on Young Adults, their Families and the Health System.
    NSW Health1 Jul 2020
    People funded by this grant:
    • Celermajer D
  • GRANT
    An Australian Study of the Outcomes and Burden of Congenital Heart Disease
    Department of Health and Aged Care (Federal)26 Jun 2020 - 31 Dec 2026
    People funded by this grant:
    • Disney P,
    • Cheung M,
    • Selbie L,
    • Celermajer D,
    • Scuffham PA
  • GRANT
    Congenital Heart Fitness Intervention Trial: CH-FIT
    Department of Health and Aged Care (Federal)1 Jan 2020
    People funded by this grant:
  • GRANT
    Cardiology Rapid Access Clinics
    Department of Health and Aged Care (Federal)1 Jan 2018
    People funded by this grant:
  • GRANT
    PRT MEDIC: Progressive Resistance Training for MEtabolic Syndrome and Depression Integrated Care: A Randomised Controlled Trial
    Diabetes Australia2 Jan 2017 - 31 Dec 2017
    People funded by this grant:
  • GRANT
    Development and validation of a pediatric transfer function for deriving central blood pressure from radial artery tonometry in children
    National Heart Foundation of Australia1 Jan 2016
    People funded by this grant:
    • Celermajer D,
    • Ayer J,
    • Qasem A,
    • Avolio A,
    • Butlin M
  • GRANT
    Evaluation and optimisation of rapid access cardiology models of care
    National Health and Medical Research Council (NHMRC)1 Jan 2016 - 31 Dec 2018
    People funded by this grant:
    • Brieger D,
    • Kritharides L,
    • Lowe H,
    • Celermajer D,
    • Thiagalingam A
  • GRANT
    Novel, prognostic MRI parameters in pulmonary hypertension
    National Heart Foundation of Australia1 Jan 2015
    People funded by this grant:
  • GRANT
    Premium mainframe ultrasound machine
    National Health and Medical Research Council (NHMRC)1 Jan 2015
    People funded by this grant:
  • GRANT
    National Health and Medical Research Council1 Jan 2014 - 31 Dec 2019
    People funded by this grant:
    • d'Acoz YD,
    • Dalziel K,
    • Cheung M,
    • Kasparian N,
    • Iyengar A
  • GRANT
    The Australia and New Zealand Fontan Registry: The ideal model of care to improve the adult life of children born with congenital heart disease
    National Health and Medical Research Council (NHMRC)1 Jan 2014
    People funded by this grant:
    • dUdekem dAcoz Y,
    • Gentles T,
    • McNeil JJ,
    • Winlaw D,
    • Kasparian N
  • GRANT
    Atherosclerosis - the key roles of HDL, cell cholesterol metabolism and vascular function
    National Health and Medical Research Council (NHMRC)1 Jan 2013
    People funded by this grant:
    • Rye K-A,
    • Barter P,
    • Celermajer D,
    • Jessup W,
    • Kritharides L
  • GRANT
    Atherosclerosis - the key roles of HDL, cell cholesterol metabolism and vascular function
    National Health and Medical Research Council (NHMRC)1 Jan 2013 - 31 Dec 2017
    People funded by this grant:
    • Celermajer D,
    • Rye K-A,
    • Kritharides L,
    • Jessup W,
    • Barter P
  • GRANT
    Screening of Fontan patients in Australia & New Zealand for long-term liver and kidney damage
    National Health and Medical Research Council (NHMRC)1 Jan 2013
    People funded by this grant:
    • Celermajer D
  • GRANT
    CardioCAPS: Determining the effects of the transition through puberty on vascular structure and function at age 14 years
    The Financial Markets Foundation for Children1 Jul 2012
    People funded by this grant:
  • GRANT
    CSANZ Res Sship Choudhary
    Cardiac Society of Australia & New Zealand (CSANZ)1 Jan 2012
    People funded by this grant:
    • Celermajer D
  • GRANT
    NOVEL NON-INVASIVE METHODS FOR THE EARLY DETECTION OF PULMONARY VASCULAR DISEASE
    National Health and Medical Research Council (NHMRC)1 Jan 2012 - 31 Dec 2016
    People funded by this grant:
  • GRANT
    Congenital and inherited heart diseases: towards a comprhensive life management plan
    National Heart Foundation of Australia1 Jun 2010
    People funded by this grant:
    • Winlaw D,
    • Celermajer D
  • GRANT
    Dr Berni Changsiri part-time PhD candidates project: Indoleamine 2,3-dioxgenase in the novel regulation of vascular tone :
    Pfizer Australia Pty Ltd1 Jan 2010
    People funded by this grant:
    • Celermajer D,
    • Stocker R