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DrConstance Bailey

Senior Lecturer

Faculty of Science

Orcid identifier0000-0002-4668-7245 (opens in a new tab)⁠
  • Senior Lecturer
    Faculty of Science

Research projects & supervision summary

  • Development of cell free expression tools for prototypying pathway design
  • Genetic tool development for heterologous expression in Actinobacteria and Myxobacteria
  • Polyketide synthase and non-ribosomal peptide synthetase enzymology
  • Directed evolution for late stage functionalization of natural product scaffolds
  • Heterologous expression of biosynthetic pathways
  • Discovery and development of natural product leads that target the cell surface of antimicrobially resistant pathogens

RESEARCH PROJECTS & ACTIVITIES

  • RESEARCH-BASED DEGREE SUPERVISION
    A cell free strategy for developing biocatalytic transformations from RiPPs.
  • RESEARCH-BASED DEGREE SUPERVISION
    building a cell free expression platform based on Myxobacteria Sorangium cellulosum
  • RESEARCH-BASED DEGREE SUPERVISION
    CAPTURE Biosynthetic Gene Clusters from Actinokineospora sp. and Research on Natural Products
  • RESEARCH-BASED DEGREE SUPERVISION
    Developing a biocatalytic toolkit to expand the chemical diversity of bioactive molecules
  • RESEARCH-BASED DEGREE SUPERVISION
    Developing molecular cloning tool for Streptomyces based on IS110 transposable element
  • RESEARCH-BASED DEGREE SUPERVISION
    Development of a Novel Inhibitor for FANCM-RMI
  • RESEARCH-BASED DEGREE SUPERVISION
    Development of a Pseudomonas putida cell-free protein synthesis system for PKS or NRPS expression with Genome Mining.
  • RESEARCH-BASED DEGREE SUPERVISION
    Engineering flavin dependent tryptophan halogenases to expand antimicrobial compound diversity
  • RESEARCH-BASED DEGREE SUPERVISION
    Enzymatic Characterization of Biocatalytically Relevant Enzymes
  • RESEARCH-BASED DEGREE SUPERVISION
    Heterologous expression of lasso peptides in Streptomyces albus from actinomycetes isolated from Australian soil.
  • RESEARCH-BASED DEGREE SUPERVISION
    Peptide-based modulation of MLH1-dependent mismatch repair to improve prime editing for bone marrow failure syndrome
  • RESEARCH-BASED DEGREE SUPERVISION
    Ultra-high-throughput maturase engineering to unlock semi-synthetic darobactins for multidrug-resistant Gram-negative bacteria