ProfessorWayne Hawthorne
Professor of Transplantation
Faculty of Medicine and Health
Orcid identifier0000-0001-8638-3468 (opens in a new tab)
- Professor of TransplantationFaculty of Medicine and Health
RESEARCH INTERESTs
Professor Wayne Hawthorne’s research focuses on advancing xenotransplantation, organ perfusion and preservation, and clinical islet and pancreas transplantation. His career has focussed on continuous innovation in organ and cell transplantation, with major national and international impact across translational science, clinical practice, and global policy development.
His research programs integrate:
- Xenotransplantation: Developing safe and effective cross‑species organ and cell transplantation strategies, with a focus on immunomodulation, genetic modification of donor tissues, and global governance of clinical translation.
- Organ Perfusion & Preservation: Enhancing organ viability through novel machine‑perfusion technologies, therapeutic perfusion interventions, and diagnostics to improve transplant outcomes.
- Islet Transplantation: Advancing clinical protocols, refining isolation techniques, and driving innovations that support broader clinical access and improved long‑term graft function.
FUNDED RESEARCH
- GRANTXenotransplantation a Next Generation Cure for Diabetes using Transgenic Porcine IsletsNational Health and Medical Research Council (NHMRC)1 Jan 2025People funded by this grant:
- Hawthorne W,
- Nottle M,
- Ierino F,
- Cowan PJ
- GRANTCuring Diabetes using Transgenic Porcine Islet XenotransplantationJuvenile Diabetes Research Foundation International (JDRF)1 Feb 2024 - 31 Jan 2027People funded by this grant:
- Hawthorne W
- GRANTA single dose, globally accessible vaccine to combat emerging SARS-CoV-2 variantsDepartment of Health and Aged Care (Federal)1 Mar 2021 - 29 Feb 2024People funded by this grant:
- Triccas J,
- Britton W,
- Ferguson A,
- Steain M,
- Hansbro PM
- GRANTTransplantation of pig islets to treat type 1 diabetesNational Health and Medical Research Council (NHMRC)1 Jan 2019People funded by this grant:
- Cowan P,
- Hawthorne W
- GRANTBridging the gap in kidney transplantation using pigs as donorsNational Health and Medical Research Council (NHMRC)1 Jan 2017 - 31 Dec 2020People funded by this grant:
- Cowan P,
- Yi S,
- Hawthorne W
- GRANTGenetic modification to protect pig islets from T cell-mediated xenogeneic rejectionJuvenile Diabetes Research Foundation - JDRF (Australia)1 Jan 2017People funded by this grant:
- Hawthorne W,
- Cowan P,
- Nottle M
- GRANTCONCEPT B - Expanding the criteria for human islet transplantation by the development of a drug-free immunosuppressive protocolBreakthrough T1D (Formerly Juvenile Diabetes Research Foundation - JDRF) Australia1 Jan 2016People funded by this grant:
- Donaghue K,
- Gunton JE,
- Hawthorne W,
- Alexander S,
- O'Connell P
- GRANTA helminth-derived peptide is a novel prophylactic and therapeutic treatment for autoimmune diseaseNational Health and Medical Research Council (NHMRC)1 Jan 2015 - 31 Dec 2018People funded by this grant:
- Hawthorne W
- GRANTTransplantation of pig islets to treat diabetesNational Health and Medical Research Council (NHMRC)1 Jan 2014 - 31 Dec 2018People funded by this grant:
- Yi S,
- Hawthorne W,
- Cowan P,
- Nottle MB
- GRANTBuilding sustainable collaborations in diabetes and islet transplantation research and practice in Sydney and ShanghaiDVC International1 Jan 2013People funded by this grant:
- Alexander S,
- Hu M,
- Dai J-Y,
- O'Connell P,
- Wang W
- GRANTNew strategies to protect pig-to-human renal xenograftsNational Health and Medical Research Council (NHMRC)1 Jan 2013People funded by this grant:
- Hawthorne W
- GRANTNational Health and Medical Research Council1 Jan 2013 - 31 Dec 2017People funded by this grant:
- Cowan P,
- Nottle M,
- Hawthorne W
- GRANTSmall Rodent Airlaw Caging SystemNational Health and Medical Research Council (NHMRC)1 Jan 2012People funded by this grant:
- Fletcher J,
- Harris D,
- Hebbard L,
- Hawthorne W,
- Little D
- GRANTObjective Measurement of Physical Activity and Sedentary BehaviouNational Health and Medical Research Council (NHMRC)1 Jan 2011People funded by this grant:
- Harris D,
- Little D,
- Hawthorne W,
- Baur L,
- Cunningham AT
- GRANTThe Development of a National Centre for Clinical Islet TransplantationJuvenile Diabetes Research Foundation1 Jan 2006People funded by this grant:
- Hawthorne W,
- Wilson M,
- Dado M,
- George J,
- O'Connell P
- GRANTNon immunological barriers to successful treatment of diabetes by xenotransplantation?National Health and Medical Research Council (NHMRC)1 Jan 2003 - 31 Dec 2005People funded by this grant:
- Allen R,
- Hawthorne W,
- Chapman J,
- Moran C,
- O'Connell P
