ProfessorTrevor Hambley
Emeritus Professor
Faculty of Science
RESEARCH INTERESTs
- Medicinal inorganic chemistry, in particular, Pt anticancer drugs
- Targetted delivery of metal based anticancer agents
- Investigating the relationship between the reduction potentials of Pt(IV) complexes and their biological activity
- Investigating methods for controlling the physical and biological properties of platinum(IV) complexes
- Investigation of cobalt complexes as delivery agents for anticancer agents
- Investigating and optimizing anticancer drug penetration in solid tumours and tumour models.
FUNDED RESEARCH
- GRANTBiologically inert probes to unravel nutrient directed cellular processingAustralian Research Council (ARC)1 Mar 2022 - 31 Dec 2025People funded by this grant:
- Kaur A,
- Hambley T,
- Ryan R
- GRANTFluorescent sensing of the intracellular redox environmentAustralian Research Council (ARC)1 Jan 2018 - 31 Dec 2020People funded by this grant:
- Kaur A,
- New E,
- Hambley T
- GRANTPortable Infrared Spectroscopy Equipment for Cancer Diagnosis, Research into Prevention of Cancer by Understanding the Role of Diet, and for Drug Development and Studies on EfficacyCancer Institute NSW1 Jul 2015People funded by this grant:
- Carter E,
- Bebawy M,
- Hambley T,
- Richardson DD,
- Graeber M
- GRANTEVOS FL Auto Live Cell Imaging SystemNational Health and Medical Research Council (NHMRC)1 Jan 2015People funded by this grant:
- Mason R,
- Hambley T,
- Fraser S,
- Cook D,
- Lovicu F
- GRANTThe effect of Pt binding to CTR1 on Cu homeostasis and cell phenotypeAustralian Research Council (ARC)1 Jan 2015 - 31 Dec 2017People funded by this grant:
- New E,
- Hambley T
- GRANTPerpetual Account for Australian Synchrotron Access Programme T W HambleyAustralian Synchrotron4 Mar 2014People funded by this grant:
- Hambley T
- GRANTAustralian Research Council1 Jan 2014 - 31 Dec 2017People funded by this grant:
- Hambley T
- GRANTAustralian Research Council31 Mar 2011 - 31 Dec 2011People funded by this grant:
- Jolliffe K,
- Hambley T,
- Rendina L,
- Payne R,
- Mackay J
- GRANTDevelopment of prodrug strategies for achieving increased penetration and selective activation in solid tumoursAustralian Research Council (ARC)13 Jan 2011 - 31 Dec 2014People funded by this grant:
- Metzler-Nolte N,
- Hambley T
- GRANTInnovative Synchrotron Science - Access Program to the Australian National Beamline Facility and Cutting-Edge Beamlines at International SynchrotronsAustralian Research Council (ARC)1 Jan 2011People funded by this grant:
- Dillon CT,
- Trevitt AJ,
- Bond CS,
- Shimomura O,
- Johnston S
- GRANTRadiolabelled MMP Binding Agents for the Identification, Quantification, and Targeting of MMPs in CNS Disorders and TumoursAustralian Research Council (ARC)1 Jan 2010 - 26 Jan 2013People funded by this grant:
- Hambley T,
- Kassiou M
- GRANTAustralian Research Council22 Oct 2008 - 26 Nov 2008
- GRANTAustralian Research Council1 Jan 2008 - 31 Dec 2009People funded by this grant:
- Gaus K,
- Khachigian L,
- Kavallaris M,
- Willcox M,
- Dawes I
- GRANTRational Optimisation of the Uptake of metal-Based Anti-Cancer Agents by TumoursAustralian Research Council (ARC)1 Jan 2007 - 30 Jun 2010People funded by this grant:
- Hambley T
- GRANTFunctionalised MMP Inhibitors as Radiodiagnostic, Radiotherapeutic, and Radiation-Sensitising Agents for Metastatic CancerAustralian Research Council (ARC)1 Jan 2006 - 10 May 2009People funded by this grant:
- GRANTMetal-based Anti-inflammatory Drugs with High Efficacy and Low Side-effects (LP0453765)Nature Vet Pty Ltd10 Jun 2004 - 23 May 2008People funded by this grant:
- Kaur R,
- Stoker S,
- Lay P
- GRANTAustralian Research Council1 Mar 2003 - 28 Feb 2006People funded by this grant:
- Hambley T,
- Deacon G
- GRANTFluorescence detector for he Australian National Beamline FacilityAustralian Research Council (ARC)1 Jan 2003 - 31 Dec 2004People funded by this grant:
- Creagh DC,
- Gentle IR,
- Berry A,
- Lay P,
- Best SP
- GRANTMetals in medicineAustralian Research Council (ARC)1 Jan 2003 - 3 Dec 2004People funded by this grant:
- GRANTAustralian Research Council1 Jun 2002 - 31 May 2005People funded by this grant:
- Hambley T,
- Deacon G,
- Webster L