DrShila Ghazanfar

Senior Lecturer in School of Mathematics and Statistics

Faculty of Science

Research projects & supervision summary

1. Project title: Statistical methods for the analysis of spatial omics technologies

 

Project summary:

We invite applications for a fully funded PhD position to join an ARC-funded project developing statistical and computational methods for the analysis of emerging spatial omics technologies. These technologies map the molecular profiles of individual cells directly within tissue, revealing how cells organise, communicate and change in health and disease. As datasets become increasingly large and complex, there is a growing need for rigorous statistical approaches that can meaningfully characterise the structure of these cellular environments.

This project will focus on creating new analytical frameworks that help researchers interpret complex spatial relationships between many types of cells, compare these patterns across heterogeneous tissues, and understand how upstream processing decisions influence biological conclusions. All methods will be released as open-source software to support widespread adoption in biology, medicine and data science.

The PhD candidate will be jointly supervised by Dr Shila Ghazanfar and A/Prof Ellis Patrick and will join an active research environment spanning statistics, bioinformatics and biomedical collaboration. The School of Mathematics and Statistics and the Sydney Precision Data Science Centre offer strong mentoring, regular training activities and opportunities to connect with leading researchers in spatial omics.

This scholarship is ideal for candidates with a background in statistics, data science, computer science or bioinformatics.

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RESEARCH PROJECTS & ACTIVITIES

  • RESEARCH-BASED DEGREE SUPERVISION
    Computational methods in Transcriptomics: Analyzing Subcellular Signaling and Evaluating Generative AI for Drug Discovery
  • RESEARCH-BASED DEGREE SUPERVISION
    Deep Learning for Spatiotemporal Biological Systems
  • RESEARCH-BASED DEGREE SUPERVISION
    Dissecting cancer and immune vulnerabilities in advanced melanoma patients treated with immunotherapy
  • RESEARCH-BASED DEGREE SUPERVISION
    Effectively Leveraging Temporally Sampled Spatial Omics Data in Health and Disease
  • RESEARCH-BASED DEGREE SUPERVISION
    Methods towards precision bioinformatics in single cell era
  • RESEARCH-BASED DEGREE SUPERVISION
    Social Media for cells? Network inference for evaluating the relationship between cells.
  • RESEARCH-BASED DEGREE SUPERVISION
    Supervised Dimension Reduction for Single-Cell Gene Expression Data