DrSanjay Swaminathan
Clinical Associate Professor
Faculty of Medicine and Health
- Clinical Associate ProfessorFaculty of Medicine and Health
RESEARCH INTERESTs
Dr Swaminathan's research interests have focused on how viral infections affect the immune system. The EBV Molecular Laboratory (which he heads) is dedicated to understanding the molecular underpinnings of how EBV infection modulates the expression of at risk genes in the development of autoimmune disease. We use a range of experimental and in-silico methodologies to study EBV infection and we envisage that our work will lead to novel therapeutics targeting viral proteins that treat or prevent immune mediated diseases.
He is particularly interested in exploring the role between non-coding RNAs (such as miRNAs) and key immune proteins that may lead to immune dysregulation. Other projects in the lab are aimed at using siRNAs to knock down key viral proteins to see if this reduces the expression of at risk genes that lead to autoimmunity. Understanding the gender disparity is also one of the key goals of the laboratory.
FUNDED RESEARCH
- GRANTTargeting EBV factors to inhibit expansion of EBV infected B cells as a proof of concept therapeutic strategy in MSMultiple Sclerosis Research Australia1 Jan 2021People funded by this grant:
- Afrasiabi A,
- Parnell G,
- Swaminathan S
- GRANTTargeting Epstein Barr Virus transcription factor EBNA2 to control MSMultiple Sclerosis Research Australia1 Jan 2020People funded by this grant:
- Parnell G,
- Swaminathan S,
- Booth D
- GRANTHow the EBV transcription factor EBNA2 regulates MS riskMultiple Sclerosis Research Australia1 Jan 2019People funded by this grant:
- Parnell G,
- Swaminathan S,
- Schibeci S
- GRANTInvestigating the role of Epstein-Barr virus encoded microRNAs (miRNAs) in B cells, NK cells and T cells for conferring risk in developing multiple sclerosisMultiple Sclerosis Research Australia1 Jan 2015People funded by this grant:
- Booth D,
- Swaminathan S