DrSanjay Swaminathan

Clinical Associate Professor

Faculty of Medicine and Health

  • Clinical Associate Professor
    Faculty of Medicine and Health

RESEARCH INTERESTs

Dr Swaminathan's research interests have focused on how viral infections affect the immune system. The EBV Molecular Laboratory (which he heads) is dedicated to understanding the molecular underpinnings of how EBV infection modulates the expression of at risk genes in the development of autoimmune disease. We use a range of experimental and in-silico methodologies to study EBV infection and we envisage that our work will lead to novel therapeutics targeting viral proteins that treat or prevent immune mediated diseases.

He is particularly interested in exploring the role between non-coding RNAs (such as miRNAs) and key immune proteins that may lead to immune dysregulation. Other projects in the lab are aimed at using siRNAs to knock down key viral proteins to see if this reduces the expression of at risk genes that lead to autoimmunity. Understanding the gender disparity is also one of the key goals of the laboratory.

FUNDED RESEARCH

  • GRANT
    Targeting EBV factors to inhibit expansion of EBV infected B cells as a proof of concept therapeutic strategy in MS
    Multiple Sclerosis Research Australia1 Jan 2021
    People funded by this grant:
  • GRANT
    Targeting Epstein Barr Virus transcription factor EBNA2 to control MS
    Multiple Sclerosis Research Australia1 Jan 2020
    People funded by this grant:
  • GRANT
    How the EBV transcription factor EBNA2 regulates MS risk
    Multiple Sclerosis Research Australia1 Jan 2019
    People funded by this grant:
  • GRANT
    Investigating the role of Epstein-Barr virus encoded microRNAs (miRNAs) in B cells, NK cells and T cells for conferring risk in developing multiple sclerosis
    Multiple Sclerosis Research Australia1 Jan 2015
    People funded by this grant:
    • Booth D,
    • Swaminathan S