ProfessorRobert Sanders

Nuffield Chair of Anaesthetics

Faculty of Medicine and Health

RESEARCH INTERESTs

My passion is translational medicine, understanding mechanisms of disease to improve patient outcomes and experience. Neuropsychiatric disorders, such as delirium, dementia and schizophrenia, have massive financial, personal and societal impact and also limited therapeutic options. My focus is innovative investigation into the underlying pathogenic mechanisms to identify novel therapeutics. We apply novel disease models inspired from theoretical neuroscience, and supported by empirical data, as a critical principle of our approach. The intent is to significantly disrupt fields that have failed produce therapies despite years of research.

My laboratory is also interested in the mechanisms of consciousness and, in particular, sensory perception. The critical purpose of anaesthesia (and sleep), is to become disconnected from the external world, yet the mechanisms of sensory disconnection and experience remain unclear. We aim to illuminate these mechanisms, not only in the name of scientific discovery, but also to yield new approaches to providing anaesthesia,

FUNDED RESEARCH

  • GRANT
    Mitigating Delirium with Fluvoxamine Treatment for Non-Cardiac Surgery (MD FluNCS): Feasibility Trials & Mechanistic Insights
    National Institutes of Health (USA)1 Jun 2025
    People funded by this grant:
    • Sanders R,
    • Palanca BJA
  • GRANT
    Does dexmedetomidine influence changes in serum neurofilament light following on-bypass cardiac surgery?
    Australian and New Zealand College of Anaesthetists (ANZCA)1 May 2025
    People funded by this grant:
    • Marshall TJ,
    • Sanders R
  • GRANT
    A PARADIGM SHIFT IN UNDERSTANDING ANAESTHESIA
    Australian and New Zealand College of Anaesthetists (ANZCA)1 Jan 2024
    People funded by this grant:
    • Sanders R
  • GRANT
    Clarifying the overlapping pathology of delirium and dementia
    National Institutes of Health (USA)1 Jan 2024
    People funded by this grant:
  • GRANT
    Mitigating Delirium with Fluvoxamine Treatment for Non-Cardiac Surgery (MD FluNCS): Feasibility Trials & Mechanistic Insights
    National Institutes of Health (USA)1 Jan 2024
    People funded by this grant:
    • Sanders R,
    • Palanca BJA
  • GRANT
    Dexmedetomidine in Cardiac surgical Intraoperative Drug Evaluation (DECIDE)
    National Health and Medical Research Council (NHMRC)1 Jul 2023
    People funded by this grant:
  • GRANT
    Collaboration, Mechanisms & Modulation: Improving Perioperative Brain Health
    Australia New Zealand College of Anaesthetists (ANZCA)1 Jan 2023
    People funded by this grant:
    • Sanders R
  • GRANT
    Delirium, Long-Term Cognition and the Dementia Pathological Trajectory
    National Institutes of Health (USA)1 Jan 2023
    People funded by this grant:
  • GRANT
    Clarifying the overlapping pathology of delirium and dementia
    National Institutes of Health (USA)1 Jul 2020
    People funded by this grant:
    • Sanders R
  • GRANT
    Receptors, microcircuits and hierarchical connectivity in predictive coding and sensory awareness
    National Institutes of Health (USA)1 Jul 2020
    People funded by this grant:
    • Sanders R