DrRachel O'Connell
Senior Research Fellow
Faculty of Medicine and Health
- Senior Research FellowFaculty of Medicine and Health
RESEARCH INTERESTs
Dr O’Connell’s research focuses on the design, conduct and analysis of clinical trials and observational studies across a range of clinical disciplines, including oncology, diabetes, cardiovascular disease, neonatal medicine and public health. Her work aims to generate high-quality evidence to improve patient outcomes and inform clinical practice, health policy and guideline development.
Her interests include phase II and III clinical trials, individual participant data meta-analyses, large-scale cohort studies, and the application of advanced statistical methods to complex clinical research questions. She has a particular interest in evaluating treatment efficacy and safety, identifying prognostic factors and risk predictors, and translating research findings into clinical practice.
Dr O’Connell has extensive experience in patient-reported outcomes and quality-of-life research, including the development and validation of symptom and quality-of-life measures. She is also interested in statistical methodology and its application to improving the design, analysis and interpretation of clinical research.
Through multidisciplinary collaborations with national and international researchers, clinicians and trial groups, her research contributes to advancing evidence-based healthcare and improving outcomes across diverse patient populations.
Rachel is a member of the Sydney Clinical Trials Centre, a Flagship Centre in the Faculty of Medicine and Health.
FUNDED RESEARCH
- GRANTNSAID administration Or Theatre Benzodiazepine Avoidance for Delirium & Days Alive and at HomeMedical Research Future Fund1 Mar 2026 - 31 May 2028People funded by this grant:
- Sanders R,
- Agar M,
- Beard D,
- Evered L,
- Lange P
- GRANTPreventing intrapartum fetal hypoxia: the iSEARCH Pre-Platform PilotDepartment of Health and Aged Care (Federal)30 Jun 2025 - 29 Jun 2026People funded by this grant:
- De Vries B,
- Gordon A,
- Dickson M,
- O'Connell R,
- Robledo K
- GRANTDigital solutions for heart failure best practice careDepartment of Health and Aged Care (Federal)1 Jun 2021 - 31 Jul 2025People funded by this grant:
- Macdonald P,
- Kilov G,
- O'Connell R,
- Ferguson C,
- Ryan C
- GRANTPARAGON-II: Phase 2 basket study of an ARomatase inhibitor plus PI3KCA inhibitor or CDK4/6 inhibitor in women with hormone receptor positive recurrent/metastatic Gynaecological NeoplasmsDepartment of Health and Aged Care (Federal)1 Jun 2020 - 31 May 2026People funded by this grant:
- O'Connell R,
- Loi S,
- Meniawy T,
- Goh J,
- Davis AJ
- GRANTPAEAN: Preventing adverse outcomes of neonatal hypoxic ischaemic encephalopathy with erythropoietin: A randomised controlled multicentre clinical trialCerebral Palsy Alliance Research Foundation1 May 2019People funded by this grant:
- Askie L,
- Hunt R,
- Novak I,
- Battin M,
- Wagh D
- GRANTDoes Palliative Chemotherapy Palliate Measuring symptom benefit in recurrent ovarian cancer using patient reported outcomes: The Symptom Benefit StudyNational Health and Medical Research Council (NHMRC)1 Jan 2014 - 31 Dec 2015People funded by this grant:
- Ledermann J,
- O'Connell R,
- Oza A,
- King M,
- Lee CK
- GRANTPreventing Adverse Outcomes of Neonatal Encephalopathy with Erythropoietin - the PAEAN StudyNational Health and Medical Research Council (NHMRC)1 Jan 2014 - 31 Dec 2018People funded by this grant:
- O'Connell R,
- Badawi N,
- Askie L,
- Battin M,
- Jacobs SE
- GRANTNational Health and Medical Research Council1 Jan 2013 - 31 Dec 2018People funded by this grant:
- Neale R,
- Pols JVD,
- O'Connell R,
- Venn A,
- Armstrong B