Skip to main contentAll people

Professor EmeritusNicholas Manolios

Honorary Professor

Faculty of Medicine and Health

Orcid identifier0000-0002-6525-7830 (opens in a new tab)⁠
  • Honorary Professor
    Faculty of Medicine and Health

RESEARCH INTERESTs

Professor Nicholas Manolios research interests are: (i) Structure and assembly of the T-cell antigen receptor, in particular, its role in the predisposition and causation of auto-immune and inflammatory rheumatic disorders, and (ii) Structure-function relationships of T cell assembly and T-cell activation, and how synthetic peptides may be used as therapeutic agents to suppress inflammation. Recent research hs focussed on drug delivery.

FUNDED RESEARCH

  • GRANT
    Determining the scope of action of a novel immunomodulatory peptide
    Rebecca L Cooper Medical Research Foundation1 Apr 2016
    People funded by this grant:
    • Manolios N,
    • Limaye A,
    • Ali M
  • GRANT
    Retroviral gene expression of immunosuppressive peptides in the prevention of islet transplantation rejection in mice.
    Wenkart Foundation1 Feb 2010
    People funded by this grant:
    • Wong M,
    • Manolios N
  • GRANT
    Application of a cyclic peptide (C1) for the treatment of T-cell mediated inflammatory disease
    Royal Australasian College of Physicians1 Jan 2009
    People funded by this grant:
    • Manolios N
  • GRANT
    Peptide-Lipid interactions: Effect of cellular milieu on biophysical properties of transmembrane peptides
    DVC Research1 Jan 2009
    People funded by this grant:
    • Manolios N
  • GRANT
    Not Known - To be advised
    Rebecca L Cooper Medical Research Foundation1 Jan 2006
    People funded by this grant:
    • Manolios N
  • GRANT
    Natural Killer Cell Transmembrane Peptides - evaluation for Clinical Application
    Glaxo SmithKline Aust Pty Ltd1 Jan 2003
    People funded by this grant:
    • Kola R,
    • Jonak Z,
    • Manolios N
  • GRANT
    Development of new anti-arthritic drugs
    Clive & Vera Ramaciotti Foundation1 Jan 2002
    People funded by this grant:
    • Manolios N
  • GRANT
    Evaluation of specificity, mechanisms of action and therapeutic use of peptides that disrupt T-cell antigen receptor
    National Health and Medical Research Council (NHMRC)1 Jan 2000
    People funded by this grant:
    • Manolios N
  • GRANT
    T cell receptor peptide treatment in experimental allergic encephalomyelitis
    National Multiple Sclerosis Society (USA)1 Jan 2000
    People funded by this grant:
  • GRANT
    Transgenomic WAVE 2100 denaturing HPLC system for DNA variant analysis
    National Health and Medical Research Council (NHMRC)1 Jan 2000
    People funded by this grant:
    • Farrell G,
    • Clarke C,
    • Kirk J,
    • Leary J,
    • Mitchell P