DrKavitha Gowrishankar

Senior Lecturer - Immunology

Faculty of Medicine and Health

  • Senior Lecturer - Immunology
    Faculty of Medicine and Health

Research projects & supervision summary

Engineering safe and effective CARs (chimeric antigen receptors) to drive cancer treatment

Development of CARs for paediatric solid tumours (sarcoma, brain) and adult haematological malignancies (leukaemia, lymphoma, multiple myeloma)

Development of transgenic T cell receptors for both haematological and solid organ malignancies

RESEARCH PROJECTS & ACTIVITIES

  • RESEARCH-BASED DEGREE SUPERVISION
    Chimeric Antigen Receptor T Cells for Invasive Fungal Infections Using a Novel Gene Modification Strategy
  • RESEARCH-BASED DEGREE SUPERVISION
    Designing novel T-cell therapies for acute myeloid leukaemia utilising native and chimeric receptors
  • RESEARCH-BASED DEGREE SUPERVISION
    Engineering Enhanced T-cell Receptors and Chimeric Antigen Receptors for Improved Oncology Therapeutics
  • RESEARCH-BASED DEGREE SUPERVISION
    Generating combinatorial TCR T-cell therapy for paediatric malignancies
  • RESEARCH-BASED DEGREE SUPERVISION
    Generation of transgenic T cell receptor T cells recognising fungal antigens for the treatment of invasive fungal infections in patients with haematological cancers.
  • RESEARCH-BASED DEGREE SUPERVISION
    Investigating the tumour suppressive mechanisms and functional roles of X-linked epigenetic regulators in human melanoma
  • RESEARCH-BASED DEGREE SUPERVISION
    Moving from Transposons/Transposase system to CRISPR/Cas9 to produce an Off the Shelf CAR T-cell
  • RESEARCH-BASED DEGREE SUPERVISION
    Next Generation Detection: Novel Assays to Evaluate CAR T Therapy Response in 3D Sarcoma Models
  • RESEARCH-BASED DEGREE SUPERVISION
    Novel CAR T-cells to treat soft tissue sarcoma
  • RESEARCH-BASED DEGREE SUPERVISION
    Novel T cell therapies against acute myeloid leukaemia: Enhancing the graft-versus-leukemia effect through characterisation and expansion of T cells targeting leukemia associated antigens
  • RESEARCH-BASED DEGREE SUPERVISION
    The proteomic, immune, and antigenic profiling of colorectal cancer for the design of CAR-T cell therapies
  • RESEARCH-BASED DEGREE SUPERVISION
    Trafficking of Tumour Associated Antigens in Brain Cancer and Implications for Therapy