DrKavitha Gowrishankar
Senior Lecturer - Immunology
Faculty of Medicine and Health
Orcid identifier0000-0002-8616-6727 (opens in a new tab)
- Senior Lecturer - ImmunologyFaculty of Medicine and Health
Research projects & supervision summary
Engineering safe and effective CARs (chimeric antigen receptors) to drive cancer treatment
Development of CARs for paediatric solid tumours (sarcoma, brain) and adult haematological malignancies (leukaemia, lymphoma, multiple myeloma)
Development of transgenic T cell receptors for both haematological and solid organ malignancies
RESEARCH PROJECTS & ACTIVITIES
- RESEARCH-BASED DEGREE SUPERVISIONChimeric Antigen Receptor T Cells for Invasive Fungal Infections Using a Novel Gene Modification Strategy
- RESEARCH-BASED DEGREE SUPERVISIONDesigning novel T-cell therapies for acute myeloid leukaemia utilising native and chimeric receptors
- RESEARCH-BASED DEGREE SUPERVISIONEngineering Enhanced T-cell Receptors and Chimeric Antigen Receptors for Improved Oncology Therapeutics
- RESEARCH-BASED DEGREE SUPERVISIONGenerating combinatorial TCR T-cell therapy for paediatric malignancies
- RESEARCH-BASED DEGREE SUPERVISIONGeneration of transgenic T cell receptor T cells recognising fungal antigens for the treatment of invasive fungal infections in patients with haematological cancers.
- RESEARCH-BASED DEGREE SUPERVISIONInvestigating the tumour suppressive mechanisms and functional roles of X-linked epigenetic regulators in human melanoma
- RESEARCH-BASED DEGREE SUPERVISIONMoving from Transposons/Transposase system to CRISPR/Cas9 to produce an Off the Shelf CAR T-cell
- RESEARCH-BASED DEGREE SUPERVISIONNext Generation Detection: Novel Assays to Evaluate CAR T Therapy Response in 3D Sarcoma Models
- RESEARCH-BASED DEGREE SUPERVISIONNovel CAR T-cells to treat soft tissue sarcoma
- RESEARCH-BASED DEGREE SUPERVISIONNovel T cell therapies against acute myeloid leukaemia: Enhancing the graft-versus-leukemia effect through characterisation and expansion of T cells targeting leukemia associated antigens
- RESEARCH-BASED DEGREE SUPERVISIONThe proteomic, immune, and antigenic profiling of colorectal cancer for the design of CAR-T cell therapies
- RESEARCH-BASED DEGREE SUPERVISIONTrafficking of Tumour Associated Antigens in Brain Cancer and Implications for Therapy