Associate ProfessorJustin Wong

Associate Professor

Faculty of Medicine and Health

RESEARCH INTERESTs

Dr. Justin Wong has a very strong interest in gene expression regulation. Having completed his PhD with high profile papers related to germline epimutation and cancers (New England Journal of Medicine, Cancer Cell, Gut), he has studied the role of non-coding RNA, RNA modifications and alternative splicing in normal physiology and disease. His current research topics are:

1. The mechanisms of intron retention in the development of white blood cells (Follow-up of his paper in Cell, Nature Communications, Nucleic Acids Research, Immunology).

2. The role of intron retention in acute myeloid leukaemia.

3. The role of RNA modification in white blood cell differentiation and cancer.

4. The role of RNA modification in macrophage development and function.

5. The role of RNA modification in smooth muscle cell plasticity.

FUNDED RESEARCH

  • GRANT
    Australian Research Council20 Feb 2026 - 19 Feb 2029
    People funded by this grant:
    • Wong J,
    • Schmitz U
  • GRANT
    Linking altered RNA modification in untranslated regions to cancer pathogenesis
    National Health and Medical Research Council (NHMRC)1 Jan 2025
    People funded by this grant:
    • Wong J,
    • Sutton G
  • GRANT
    Novel role of RNA methylation in neuronal homeostasis
    Australian Research Council (ARC)9 Nov 2023 - 31 Dec 2026
    People funded by this grant:
    • Wong J
  • GRANT
    Senior Lecturer in Cancer
    Faculty of Medicine and Health1 Jan 2023
    People funded by this grant:
    • Wong J
  • GRANT
    Targeting RNA in vascular smooth muscle cells to treat aortic aneurysms
    NSW Health1 Mar 2022
    People funded by this grant:
    • Lee Q,
    • Wong J,
    • Hambly B,
    • Song R,
    • Bannon P
  • GRANT
    Alternative splicing: A novel target to improve outcomes in acute myeloid leukaemia
    National Health and Medical Research Council (NHMRC)1 Jan 2022
    People funded by this grant:
    • Johnstone R,
    • Wong J,
    • Wong A,
    • Rasko J
  • GRANT
    Deciphering the role of TET2-HDAC4 in the regulation of vascular smooth muscle plasticity
    National Health and Medical Research Council (NHMRC)1 Jul 2020
    People funded by this grant:
    • Wong J,
    • Liu R
  • GRANT
    Deciphering the role of aberrant RNA modification to improve therapy of acute myeloid leukaemia
    Tour de Cure Ltd1 Jan 2019
    People funded by this grant:
    • Wong J
  • GRANT
    SOAR Fellowship
    DVC Research1 Jan 2019
    People funded by this grant:
    • Wong J
  • GRANT
    The role of altered RNA N6-adenosine m6A methylation in acute myeloid leukaemia
    Cancer Council NSW1 Jan 2019
    People funded by this grant:
    • Rasko J,
    • Wong J
  • GRANT
    Defining the role of aberrant splicing intron retention in the development and maintenance of acute myeloid leukaemia
    Cancer Institute NSW1 Jan 2018
    People funded by this grant:
    • Rasko J,
    • Wong J
  • GRANT
    New Initiatives in Basic and Applied Medical Research
    Philip Bushell Foundation1 Jan 2018
    People funded by this grant:
  • GRANT
    National Health and Medical Research Council1 Jan 2018 - 31 Dec 2020
    People funded by this grant:
    • Roediger B,
    • Beverdam A,
    • Wong J,
    • Gros GL,
    • Wilkins M
  • GRANT
    Deciphering the role of DNA methylation in the regulation of alternative splicing
    National Health and Medical Research Council (NHMRC)1 Jan 2017 - 31 Dec 2020
    People funded by this grant:
    • Wong J,
    • Rasko J,
    • Lister R
  • GRANT
    National Health and Medical Research Council1 Jan 2017 - 31 Dec 2019
    People funded by this grant:
    • Wong J
  • GRANT
    National Health and Medical Research Council1 Jan 2017 - 31 Dec 2021
    People funded by this grant:
    • Rasko J,
    • Wong J
  • GRANT
    Investigating widespread regulation of gene expression through intron retention
    National Health and Medical Research Council (NHMRC)1 Jan 2015 - 31 Dec 2017
    People funded by this grant:
    • Ritchie W,
    • Rasko J,
    • Wong J
  • GRANT
    Linking mutations and epigenetic silencing ofsplicing factors to aberrant splicing in acutemyeloid leukaemia
    Cancer Institute NSW1 Jan 2014
    People funded by this grant:
    • Wong J