ProfessorJennifer Gamble

Wenkart Chair of the Endothelium

Faculty of Medicine and Health

RESEARCH INTERESTs

Professor Jennifer Gamble is an internationally recognized research leader in the field of endothelial cell function.

Her interests lie in understanding endothelial cell function particularly in the area of inflammation, and how dysfunction can influence disease. Her initial publication in this area established the endothelium as a dynamic organ, central to the control of inflammatory processes.

She is a Editor for Aging Cell and Senior Editor for Vascular Biology Journal.

She was a founding member of the Australian Vascular Biology Society.

She was recently Co-Chair of the World Congress on Inflammation, Sydney 2019

FUNDED RESEARCH

  • GRANT
    Inhibiting vascular leak using new molecular glues
    National Heart Foundation of Australia1 Jan 2025
    People funded by this grant:
  • GRANT
    The Ageing Endothelium
    NSW Health1 Mar 2024
    People funded by this grant:
    • Gamble J
  • GRANT
    New Strategies for Early Treatment of Alzheimers Disease
    Philip Bushell Foundation1 Jan 2021
    People funded by this grant:
    • Ting KK,
    • Gamble J
  • GRANT
    Endothelial Cell Senescence and Alzheimers Disease
    National Health and Medical Research Council (NHMRC)1 Jan 2020
    People funded by this grant:
    • Ting KK,
    • Gamble J
  • GRANT
    Therapeutic ultrasound for the treatment of brain disorders
    Department of Health and Aged Care (Federal)1 Jul 2019
    People funded by this grant:
    • Gamble J
  • GRANT
    Economic and versatile single-cell preparation system for shared use, in the Multi-Disciplinary Sydney Cytometry Facility. From Cancer to COVID-19.
    National Health and Medical Research Council (NHMRC)1 Jan 2019
    People funded by this grant:
  • GRANT
    Manipulation of the Ageing Endothelium
    NSW Health1 Jan 2019
    People funded by this grant:
    • Gamble J
  • GRANT
    Real-time image-guided Optical Coherence Tomography 2 (OCT2)
    National Health and Medical Research Council (NHMRC)1 Jan 2019
    People funded by this grant:
  • GRANT
    Modulation of endothelial junctions as selective immunotherapy
    National Health and Medical Research Council (NHMRC)1 Jan 2018 - 31 Dec 2020
    People funded by this grant:
    • Gamble J,
    • Weninger W
  • GRANT
    "Beyond the tape measure" - measuring the impact of abnormal flow dynamics on dilation of the ascending aorta
    National Health and Medical Research Council (NHMRC)1 Jan 2017 - 31 Dec 2020
    People funded by this grant:
  • GRANT
    Sensitizing tumours to immunotherapy: Development of an RNA-based therapeutic for pancreatic adenocarcinoma that targets the immunosuppressive tumour microenvironment
    National Health and Medical Research Council (NHMRC)1 Jan 2017 - 31 Dec 2017
    People funded by this grant:
    • Begley CG,
    • Gamble J,
    • Biankin A,
    • Vadas M
  • GRANT
    A new therapy for pancreatic cancer that improves tumour microenvironment and immune cell penetration
    PanKind Australian Pancreatic Cancer Foundation Ltd1 Jan 2016
    People funded by this grant:
    • Vadas M,
    • Gamble J
  • GRANT
    Role of sphingolipid signalling in hepatic insulin resistance and its application in prediction of risk for type 2 diabetes and prediabetes
    National Health and Medical Research Council (NHMRC)1 Jan 2016 - 31 Dec 2020
    People funded by this grant:
    • Xia P,
    • Xia M,
    • Gamble J,
    • Lin H,
    • McCaughan GW
  • GRANT
    Novel therapy approaches for diabetes and its liver and heart complications
    Rebecca L Cooper Medical Research Foundation2 Feb 2015
    People funded by this grant:
  • GRANT
    Imaging cell and tissue architecture using confocal and super-resolution microscopy
    Australian Research Council (ARC)1 Jan 2014 - 31 Dec 2014
    People funded by this grant:
  • GRANT
    The immunomodulatory and angiogenic role of bone marrow-derived endothelial progenitor cells in chronic liver disease
    Department of Industry, Science and Resources1 Jan 2014
    People funded by this grant:
    • Trehanpati N,
    • Seth D,
    • Duly A,
    • Kaur S,
    • Sarin S
  • GRANT
    To support research Endothelium Vascular Biology Program
    Sydney Medical School1 Jan 2014
    People funded by this grant:
    • Gamble J
  • GRANT
    Leica PowerMosaic plus microsope upgrade for flexible, high-resolution slide scanning
    National Health and Medical Research Council (NHMRC)1 Jan 2013
    People funded by this grant:
  • GRANT
    Normalisation of tumour angiogenic vessels by a novel miRNA inhibitor
    University of Sydney - Sydney Catalyst Translational Cancer Research1 Jan 2013
    People funded by this grant:
    • Vadas M,
    • Gamble J
  • GRANT
    miRNAs and Cardiovascular Disease
    National Heart Foundation of Australia1 Jan 2012
    People funded by this grant:
    • Gamble J,
    • Vadas M
  • GRANT
    Automated storage, retrieval, and UV imaging system
    National Health and Medical Research Council (NHMRC)1 Jan 2011
    People funded by this grant:
    • Xia P,
    • Jormakka M,
    • Rasko J,
    • Vadas M,
    • Clarke R
  • GRANT
    Senescence and Cardiovascular Disease
    National Heart Foundation of Australia1 Jan 2011
    People funded by this grant:
    • Vadas M,
    • Gamble J
  • GRANT
    High speed 3D live cell imaging of cancer genesis, growth, metastasis and death.
    Cancer Institute NSW1 Jul 2010
    People funded by this grant:
    • Rasko J,
    • McCaughan GW,
    • Richardson DD,
    • Weninger W,
    • Fazekas de St Groth BD
  • GRANT
    Inflammation, Angiogenesis and Cancer
    National Health and Medical Research Council (NHMRC)1 Jan 2010 - 31 Dec 2014
    People funded by this grant:
  • GRANT
    New Surfaces for the Control of Endothelial Cell Function: Application in the Design of Biocompatible Stents
    Australian Research Council (ARC)1 Jan 2010
    People funded by this grant: