Associate ProfessorEleanor Drummond

Dr Drummond’s research focuses on understanding the cause of neurodegenerative diseases, particularly Alzheimer’s Disease and primary tauopathies such as Progressive Supranuclear Palsy, Corticobasal Degeneration and Pick's Disease.
 
She has a keen interest in mapping all protein changes linked to these diseases in human brain tissue. She has developed new proteomics techniques that allows the localised analysis of proteins present in specific populations of cells or neuropathological lesions present in disease (e.g. amyloid plaques or neurofibrillary tangles) and that identify the protein interactors of key disease mediators such as tau and beta amyloid. She has generated the most comprehensive atlas available of all protein changes that occur throughout the progression of Alzheimer’s in human brain tissue (NeuroPro: https://neuropro.biomedical.hosting/) and has developed new cell culture approaches to determine the mechanistic role in disease for these new proteins identified in her proteomics studies. She is currently exploring the therapeutic potential of targeting these newly identified brain protein changes to treat Alzheimer’s disease and is examining whether these protein changes are new potential blood biomarkers for Alzheimer’s disease.