DrMike Wu

Mike's research aims to center on clarifying the major players and mechanisms contributing to the non-reflow phenomenon in small vessels in cardiovascular ischemic diseases. This is achieved through the utilization of powerful animal models, high-end confocal imaging, and immunostaining techniques. Specifically, his focus areas include delineating the role of dying platelets in triggering remote organ injury following the initial ischemic insult, as well as investigating the novel mechanism(s) obstructing microvasculature via erythrocytes and dying endothelium in SARS-CoV-2 infected and ischemia reperfusion injured patients. Additionally, Mike's research also encompasses the discovery of the next generation of anti-coagulants with a safer bleeding profile for stroke treatment. Building on his expertise in animal models and the discovery of new occluding mechanisms, he plans to expand his research to develop new diagnostic tools for identifying potential thrombosis risks in individuals who have not exhibited any symptoms.

Furthermore, Mike aims to publish his findings in high-impact journals in the fields of hematology and immunology. To date, he has already published his work in Nature, PNAS, Nature Communications, and Science Translational Medicine.