RESEARCH INTERESTs

There is no cure for inflammatory skin diseases which are costly and debilitating. Immune suppression is the only treatment option, but current therapies are expensive, can cause serious side-effects and are not always efficacious. Dr Ashhurst's research aims to develop next generation therapeutics that are safer, readily accessible and preferentially suppress local inflammation. She is committed to interdisciplinary research to achieve translational outcomes that could not be realised within a single discipline, pursuing innovative projects in collaboration with specialists in pharmaceutical science and chemistry.

Dr Ashhurst also has expertise in inflammatory responses at the pulmonary mucosa (lungs), particularly in response to infectious diseases such as tuberculosis, which remains the world's leading infectious disease killer, and other common respiratory viral pathogens such as SARS-CoV-2, influenza and RSV. She has an interest in developing vaccines and drugs designed for inhalation.

FUNDED RESEARCH

  • GRANT
    Targeting mucosal immunity via a novel nasal subunit vaccine platform
    Australian and New Zealand Society for Immunology1 Jan 2026
    People funded by this grant:
    • Ashhurst A
  • GRANT
    NoV Flu-RSV: Nasal vaccination for Influenza and RSV
    Australian Respiratory Council7 Jan 2025
    People funded by this grant:
  • GRANT
    Development of an immune-modulating human peptide as a next generation topical therapy for inflammatory skin diseases
    National Health and Medical Research Council (NHMRC)1 Jan 2024
    People funded by this grant:
  • GRANT
    Nasal delivered COVID vaccine to block transmission of SARS-CoV-2
    NSW Health1 Jan 2023
    People funded by this grant:
  • GRANT
    A novel human peptide-based immune modulating drug to reduce severe lung inflammation
    Drug Discovery Initiative1 Jan 2022
    People funded by this grant:
    • Ashhurst A
  • GRANT
    Nasal delivered COVID vaccine to block transmission of SARS-CoV-2
    Centre for Drug Discovery Innovation1 Jan 2022
    People funded by this grant:
    • Ashhurst A
  • GRANT
    Mucosal vaccination against SARS-CoV-2 to generate protection in the upper respiratory tract
    Sydney Institute for Infectious Diseases (Sydney ID)1 Jan 2021
    People funded by this grant:
    • Ashhurst A
  • GRANT
    Targeting inflammatory skin disease using an immune-modulatory human signal peptide
    National Health and Medical Research Council (NHMRC)1 Jan 2021
    People funded by this grant:
  • GRANT
    Self-derived immunomodulatory peptide RP23 as a novel therapeutic for psoriasis
    GRAPPA - Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (USA)1 Jul 2020
    People funded by this grant:
    • Ashhurst A